Core-collapse supernovae (CCSNe) are spectacular explosions of dying massive stars and play significant roles in various astrophysical processes. It is a key topic, and still a major difficulty, to determine the progenitors of different types of CCSNe. in this talk, l will describe the general understanding on this topic from past studies and introduce our recent work in this field on a wide range of CCSN types using a combination of different techniques. Our main finding is that interacting binaries play ubiquitous roles in almost all types of CCSNe, from the H-rich Type ll-P to the H-poor Types llb/lb/lc as well as those types with strong interaction with circumstellar material. Future large-scale surveys with high spatial and temporal resolutions (such as Euclid, CSST, LSST and GOTTA) will better reveal the progenitors of CCSNe in the golden era of time-domain astronomy.
